[Changes of lung volumes and respiratory muscle strength in patients with growth hormone deficiency]. / Modificazioni dei volumi polmonari e della forza muscolare respiratoria in pazienti con deficit dell'ormone della crescita.
Ann Ital Med Int
; 10(4): 242-5, 1995.
Article
en It
| MEDLINE
| ID: mdl-8718659
ABSTRACT
The relationship between growth hormone deficiency (GHd) and ventilatory function is not well understood. We studied 7 patients with GHd since childhood who had been adequately treated with replacement therapy until cartilage fusion. Together with 7 well-matched (age and body-type) healthy control subjects, they underwent spirometry including determination of residual volume, and lung diffusing capacity. Also recorded were maximal respiratory muscle pressure during inspiration (PImax) and expiration (PEmax). Patients with GHd showed a significant reduction in total lung capacity and vital capacity while residual volume and lung diffusing capacity remained unchanged. All patients had a significant reduction of both PImax and PEmax. Previously treated adult subjects with GHd present a persistent decrease in lung mobilizing volumes associated with reduced respiratory muscle strength. These alterations may have implications in the management of GHd in adult patients.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Respiración
/
Músculos Respiratorios
/
Hormona del Crecimiento
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
It
Revista:
Ann Ital Med Int
Asunto de la revista:
MEDICINA INTERNA
Año:
1995
Tipo del documento:
Article