Mechanoreceptive afferents exhibit functionally-specific activity dependent changes in conduction velocity.
Brain Res
; 721(1-2): 91-100, 1996 May 20.
Article
en En
| MEDLINE
| ID: mdl-8793088
ABSTRACT
Impulse activity in axons generates aftereffects on membrane excitability that can alter the conduction velocity of subsequently conducted impulses. We used a computerized stimulus pattern (a 1 Hz stimulus period followed by a period of repeated short bursts at 200 Hz) to assess in vivo activity-dependent changes in conduction latency of functionally identified rat cutaneous afferents conducting in the A beta range. Several different parameters of activity dependence were measured burst supernormality, the average increase in conduction latency following conditioning with a single preceding impulse during high frequency burst stimulation; burst subnormality, the average latency increase during each burst; depression, a long-term increase in latency caused by the high frequency stimulation. The data show that different mechanosensitive A beta afferents with overlapping resting conduction velocities exhibit activity-dependent changes in conduction latency that are characteristic of their particular functions.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Mecanorreceptores
/
Conducción Nerviosa
/
Neuronas Aferentes
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Brain Res
Año:
1996
Tipo del documento:
Article
País de afiliación:
Estados Unidos