Risperidone-induced neuroleptic malignant syndrome.
Ann Pharmacother
; 30(7-8): 775-8, 1996.
Article
en En
| MEDLINE
| ID: mdl-8826559
ABSTRACT
OBJECTIVE:
To describe a patient with neuroleptic malignant syndrome (NMS) induced by risperidone, an atypical antipsychotic, and to review the available literature related to risperidone-associated NMS. DATA SOURCE Case report information was obtained from the resident physician and medical records. MEDLINE and Index Medicus were searched to obtain literature published between 1960 and 1995. DATASYNTHESIS:
We report an adolescent boy who developed NMS after treatment with risperidone. Risperidone therapy was started after unsuccessful treatment and development of extrapyramidal adverse effects with haloperidol. The patient demonstrated the classic tetrad of fever, generalized skeletal muscle rigidity, altered mental status, and autonomic dysfunction. Risperidone was discontinued and the patient recovered after a prolonged hospital course with supportive management.CONCLUSIONS:
Clinicians are cautioned about the possibility of NMS with risperidone.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Antipsicóticos
/
Risperidona
/
Síndrome Neuroléptico Maligno
Límite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
Ann Pharmacother
Asunto de la revista:
FARMACOLOGIA
/
TERAPIA POR MEDICAMENTOS
Año:
1996
Tipo del documento:
Article
País de afiliación:
Estados Unidos