Effect of corticosterone on serotonin and catecholamine receptors and uptake sites in rat frontal cortex.
Brain Res
; 728(2): 260-2, 1996 Jul 29.
Article
en En
| MEDLINE
| ID: mdl-8864491
ABSTRACT
The effects of corticosterone (1 mg/kg per day for 7 days) on serotonin 5-HT1A, 5-HT2A, 5-HT uptake sites, and alpha 2-adrenergic receptor sites were measured. Corticosterone treatment significantly decreased the number of 5-HT1A receptor sites (Bmax = 108 +/- 8.20 fmol/mg protein and 152.31 +/- 13.36 fmol/mg protein in corticosterone- and vehicle-treated rats, respectively). No significant differences were found in other measures. It is possible that corticosteroids exert some of their behavioral effects via regulation of 5-HT1A sites in frontal cortex.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Corticosterona
/
Receptores de Serotonina
/
Receptores de Catecolaminas
/
Lóbulo Frontal
Límite:
Animals
Idioma:
En
Revista:
Brain Res
Año:
1996
Tipo del documento:
Article
País de afiliación:
Estados Unidos