Drosophila melanogaster contains both X-linked and autosomal homologues of the gene encoding calcineurin B.
Gene
; 177(1-2): 149-53, 1996 Oct 24.
Article
en En
| MEDLINE
| ID: mdl-8921860
ABSTRACT
A transcription unit was identified in the 43E polytene band region of the second chromosome of Drosophila melanogaster (Dm) whose putative translation product has 85% amino acid (aa) identity with the B subunit of the calcineurin protein (CnB) from humans. Unlike the previously described intronless Dm CnB gene homologue, which is located within the 4F band region of the X chromosome, the coding region of this second CnB is found to be interrupted by three introns. Conceptual translation of both Dm CnB genes predict proteins of identical size that are 98% identical in aa sequence. Northern blot analyses indicate that Dm pupae and adults express two different CnB-encoding transcripts that are differentially regulated.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas de Unión al Calcio
/
Drosophila melanogaster
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Gene
Año:
1996
Tipo del documento:
Article
País de afiliación:
Australia