[Comparison of the therapeutic efficacy of the piperacillin/tazobactame combination vs. ampicillin and gentamycin in in the management of post-cesarean endometritis]. / Comparación de la eficacia terapéutica de piperacilina/tazobactam vs ampicilina más gentamicina en el tratamiento de endometritis poscesárea.
Ginecol Obstet Mex
; 64: 214-8, 1996 May.
Article
en Es
| MEDLINE
| ID: mdl-8925979
ABSTRACT
Traditionally obstetric infections have been treated with combination antimicrobial agents that provide coverage against aerobic and anaerobic bacteria commonly found in these infections. New antibiotics may be a monotherapy alternative for this type of infections. The objective of the study was to compare the efficacy of the agent piperacillin/tazobactam against ampicillin plus gentamicin in the treatment of postcesarean endometritis. By randomized way 14 patients were enrolled in the piperacillin/tazobactam group and 42 in the ampicillin-gentamicin group. A favorable clinical response occurred in 78.6% of piperacillin/tazobactam patients and 88.1% of ampicillin and gentamicin patients (p = NS). There was no statistically significant difference in the times to recovery and days of hospitalization between the two groups. The combination piperacillin/tazobactam did not show advantage towards the standard treatment, so combination antimicrobial agent continue been the optimal approach to the management of obstetric infection.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Penicilinas
/
Piperacilina
/
Gentamicinas
/
Cesárea
/
Ácido Penicilánico
/
Endometritis
/
Inhibidores Enzimáticos
/
Ampicilina
/
Antibacterianos
Tipo de estudio:
Clinical_trials
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
Es
Revista:
Ginecol Obstet Mex
Año:
1996
Tipo del documento:
Article