Vasculitis in systemic lupus erythematosus following intravenous immunoglobulin therapy.
Clin Exp Rheumatol
; 14(6): 673-5, 1996.
Article
en En
| MEDLINE
| ID: mdl-8978966
ABSTRACT
We describe a 6-year-old female patient with systemic lupus erythematosus (SLE) manifested mainly as steroid-dependent thrombocytopenia who developed a vasculitic appearing rash on her palms and soles following treatment with intravenous immunoglobulin (IVIg) (1 gm/kg/infusion x 2, 1 day apart). Vascular occlusion resulting in ischemic gangrene of the fore and midfeet eventually developed, necessitating bilateral amputation. This and other side effects described in SLE indicate that exacerbation of SLE, with the possibility of vasculitis, may occur following IVIg therapy.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trombocitopenia
/
Vasculitis
/
Inmunoglobulinas Intravenosas
/
Gangrena
/
Lupus Eritematoso Sistémico
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Child
/
Female
/
Humans
Idioma:
En
Revista:
Clin Exp Rheumatol
Año:
1996
Tipo del documento:
Article
País de afiliación:
Estados Unidos