B cell development and differentiation.
Curr Opin Immunol
; 9(2): 239-44, 1997 Apr.
Article
en En
| MEDLINE
| ID: mdl-9099791
ABSTRACT
The initial phases of B cell development depend on interactions between the cell surface molecules and secreted products of stromal cells with their receptor-ligand partners on lymphoid progenitors. Recent research in this area has greatly advanced our understanding of B cell development and differentiation. Antigen receptors on pre-B and B cells play key roles in the progression of this differentiation process, as revealed by targeted and inherited gene mutations that disrupt B cell development and by the transgenic repair of these mutations in mice.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Linfocitos B
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Opin Immunol
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
1997
Tipo del documento:
Article
País de afiliación:
Estados Unidos