Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue.
Mol Psychiatry
; 2(2): 133-6, 1997 Mar.
Article
en En
| MEDLINE
| ID: mdl-9106236
ABSTRACT
A profound inflammatory response is initiated immediately following traumatic brain injury (TBI) and is characterized by the release of several cytokines with pro- and anti-inflammatory functions. In order to elucidate which cytokines are released in the human brain in response to injury as well as in the peripheral compartment, IL-1, IL-6, IL-8, IL-10, TNF-alpha and TGF-beta were monitored in CSF and serum of severely brain-injured patients. Furthermore, we investigated the possible modulation of systemic reactions by IL-6 and the ability of IL-6 and IL-8 to promote the synthesis of nerve growth factor.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Daño Encefálico Crónico
/
Lesiones Encefálicas
/
Citocinas
Tipo de estudio:
Etiology_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Mol Psychiatry
Asunto de la revista:
BIOLOGIA MOLECULAR
/
PSIQUIATRIA
Año:
1997
Tipo del documento:
Article
País de afiliación:
Suiza