Simultaneous emission and transmission (SET) scanning in neurological PET studies.
J Comput Assist Tomogr
; 21(3): 487-97, 1997.
Article
en En
| MEDLINE
| ID: mdl-9135664
ABSTRACT
PURPOSE:
We evaluated the impact of simultaneous emission and transmission (SET) measurements of quantification and noise in neurological PET studies.METHOD:
Bias in SET was measured as a function of emission count rate and used to predict distortion in simulated FDG tissue curves and its effect on model parameter estimates. Studies were performed on a brain phantom and a patient to verify predicted bias and examine the effect of SET on noise.RESULTS:
In static imaging, SET underestimated tracer concentration by approximately 2%. In kinetic studies, tracer concentration was overestimated initially and underestimated during the mid to late part of the study, but bias in measurement of glucose metabolic rate was < 5% by simulation and < 10% in the patient study. SET imaging takes 10% longer than the emission part of a conventional scan to achieve comparable statistics.CONCLUSION:
Accurate neurological PET studies can be performed with SET. The relatively small bias can be predicted and potentially corrected.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Tomografía Computarizada de Emisión
Tipo de estudio:
Prognostic_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
J Comput Assist Tomogr
Año:
1997
Tipo del documento:
Article
País de afiliación:
Australia