Coagulation activation in extracorporeal hemodialysis.
Int J Artif Organs
; 20(3): 163-5, 1997 Mar.
Article
en En
| MEDLINE
| ID: mdl-9151152
ABSTRACT
The authors evaluated the behavior of protein C activity, factor X and factor VII coagulant activity and serum lipoprotein(a) before and after dialytic treatment in patients on maintenance hemodialysis. They observed depressed protein C activity that significantly (p < 0.005) increased and became normal immediately after hemodialysis while factor X and factor VII increased (p < 0.01; p < 0.05) despite heparinization together with amount of serum lipoprotein(a). In vitro incubation (30' at 37 degrees C) of uremic and healthy blood showed a decrease in serum lipoprotein(a) concentration. After heparin addition (final concentration 0.5 U/ml) lipoprotein(a) increased in the uremic blood only. The clinical and physiopathological implications of these results are discussed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Coagulación Sanguínea
/
Factor VII
/
Factor X
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Proteína C
/
Diálisis Renal
/
Lipoproteína(a)
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Int J Artif Organs
Año:
1997
Tipo del documento:
Article
País de afiliación:
Italia