[Effect of shengmaisan on serum lipid peroxidation in acute viral myocarditis].
Zhongguo Zhong Xi Yi Jie He Za Zhi
; 16(3): 142-5, 1996 Mar.
Article
en Zh
| MEDLINE
| ID: mdl-9208534
ABSTRACT
The effect of Shengmaisan (SMS) on 62 acute viral myocarditis patients and its peroxidation damage was studied. The results revealed that the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in blood were decreased and the content of malondialdehyde (MDA) in plasma was increased in acute viral myocarditis patients in comparison with the healthy controls (P < 0.001). 62 acute viral myocarditis patients were divided into two groups SMS group and placebo group. After treatment, both SOD and GSH-Px activities were increased and the level of MDA decreased (P < 0.001) in SMS group, while those in placebo group were not changed (P < 0.05). The results suggested that the myocardial damage of viral myocarditis is closely related with lipid peroxidation SMS acts as an effective free radical scavenger and anti-lipid peroxidation drug. SMS could prevent the damage of myocardia and might be taken as one of the effective therapeutic methods in treatment of acute viral myocarditis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Virosis
/
Medicamentos Herbarios Chinos
/
Peroxidación de Lípido
/
Depuradores de Radicales Libres
/
Miocarditis
Tipo de estudio:
Clinical_trials
Límite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhongguo Zhong Xi Yi Jie He Za Zhi
Asunto de la revista:
TERAPIAS COMPLEMENTARES
Año:
1996
Tipo del documento:
Article