Investigation of the selenium status of aborted calves with cardiac failure and myocardial necrosis.
J Vet Diagn Invest
; 9(2): 172-9, 1997 Apr.
Article
en En
| MEDLINE
| ID: mdl-9211237
ABSTRACT
Lesions of heart failure, specifically cardiac dilation or hypertrophy along with a nodular liver (chronic passive congestion) and ascites, have been found in 4-5% of aborted bovine fetuses. In this study, a group of 22 such fetuses was compared with groups of aborted fetuses without lesions of heart failure and with nonaborted fetuses obtained from a slaughterhouse. The fetuses were necropsied, tissues were taken for histopathology, and samples were collected for routine bacteriologic and virologic examinations. Liver and kidney tissue was saved for selenium analysis. Histopathologic examinations of myocardium of fetuses with cardiac failure revealed myocardial necrosis and mineralization in 7 fetuses, lymphocytic myocarditis in 5 fetuses, myocardial fibrosis in 5 fetuses, or no microscopic lesions in 5 fetuses. Mean liver selenium levels were 5.5 mumol/kg in the fetuses with heart lesions, 6.5 mumol/kg in the fetuses without heart lesions and 7.5 mumol/kg in fetuses from the slaughterhouse; these differences were statistically significant. The results suggest that selenium deficiency in bovine fetuses may cause myocardial necrosis and heart failure. This study also provides data on normal liver and kidney selenium levels in bovine fetuses from the analyses of 19 nonaborted fetuses.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Selenio
/
Cardiomiopatía Dilatada
/
Enfermedades de los Bovinos
/
Cardiomegalia
/
Aborto Veterinario
/
Hígado
/
Miocardio
Límite:
Animals
/
Pregnancy
Idioma:
En
Revista:
J Vet Diagn Invest
Asunto de la revista:
MEDICINA VETERINARIA
Año:
1997
Tipo del documento:
Article
País de afiliación:
Canadá