[Effects of hormone replacement treatment of menopause on the risk of venous thromboembolic disease]. / Les effets du traitement hormonal substitutif de la ménopause sur le risque de maladie thrombo-embolique veineuse.

ABSTRACT

Post-menopausal hormone replacement therapy increases the risk of venous thrombo-embolism 2- to 4-fold. The risk is highest in the beginning of the exposure to hormones and disappears rapidly after interruption of treatment. However, the increased risk remains low in absolute value and has to be weighed against coronary artery disease and post-menopausal osteoporosis.