[The possibility of the development of isosorbide dinitrate and nifedipine withdrawal syndromes in patients with stable stenocardia of effort]. / Vozmozhnost' razvitiia sindroma otmeny izosorbida dinitrata i nifedipina u bol'nykh stabil'noi stenokardiei napriazheniia.
Ter Arkh
; 69(9): 47-51, 1997.
Article
en Ru
| MEDLINE
| ID: mdl-9411826
ABSTRACT
Exercise tests were performed in 18 patients with stable angina of effort treated with isosorbide dinitrate (ID) or nifedipine (NF) to see whether sharp discontinuation of the above drugs may entail withdrawal syndrome. Exercise tolerance declined 21 and 24 hours after the last administration of NF, 13 and 18 hours after that of ID. Compared to NF, ID tolerance decreased in a less degree. Some of the patients experienced myocardial ischemia in the course of the exercise tolerance tests, there were more frequent anginal episodes, arterial pressure rose. For ID withdrawal syndrome manifested weaker than for NF.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Abstinencia a Sustancias
/
Vasodilatadores
/
Nifedipino
/
Dinitrato de Isosorbide
/
Angina de Pecho
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Aged
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Ter Arkh
Año:
1997
Tipo del documento:
Article