Functional magnetic resonance imaging of the acute effect of intravenous heroin administration on visual activation in long-term heroin addicts: results from a feasibility study.
Drug Alcohol Depend
; 49(1): 55-60, 1997 Dec.
Article
en En
| MEDLINE
| ID: mdl-9476700
ABSTRACT
This preliminary report is the first demonstration of the acute effects of diacetylmorphine (heroin) administration on functional activation in the human brain using functional magnetic resonance imaging (fMRI). Four opiate addicts who received regular prescriptions for heroin, underwent fMRI using a visual activation paradigm before and after a dose of 30 mg heroin. All four showed a decrease after the heroin dose in the extent of significant activation. This method shows promise for sequential scanning to determine brain activity in response to different drugs and routes of drug administration.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estimulación Luminosa
/
Encéfalo
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Imagen por Resonancia Magnética
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Abuso de Sustancias por Vía Intravenosa
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Dependencia de Heroína
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Drug Alcohol Depend
Año:
1997
Tipo del documento:
Article
País de afiliación:
Reino Unido
Pais de publicación:
IE
/
IRELAND
/
IRLANDA