Obstructive sleep apnea syndrome in patient with Creutzfeldt-Jakob disease. Clinical and morphological report.
Folia Neuropathol
; 35(3): 149-54, 1997.
Article
en En
| MEDLINE
| ID: mdl-9595849
ABSTRACT
We report a case of Creutzfeldt-Jakob disease (CJD) which at the beginning of the disease presented clinical syndrome of progressive supranuclear palsy. Rapid intellectual deterioration, supranuclear palsy, postural instability and myoclonic jerks suggested clinical diagnosis of CJD. After five months suffering from the disease patient developed obstructive sleep apnea syndrome (OSAS) confirmed by serial polysomnograms. OSAS is discussed in the context of the localization of histopathological findings and possible involvement of central autonomic structures. The main structures affected by spongiosis and astrogliosis were cortex, thalamus, basal ganglia and midbrain. OSAS was found as another sleep disturbance in CJD apart from insomnia and sleep-wake cycle abnormalities.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndromes de la Apnea del Sueño
/
Síndrome de Creutzfeldt-Jakob
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Folia Neuropathol
Asunto de la revista:
NEUROLOGIA
/
PATOLOGIA
Año:
1997
Tipo del documento:
Article
Pais de publicación:
PL
/
POLAND
/
POLONIA
/
POLÔNIA