Kappa light chain deposition disease of the liver.
Eur J Gastroenterol Hepatol
; 10(5): 429-30, 1998 May.
Article
en En
| MEDLINE
| ID: mdl-9619391
ABSTRACT
We report the case of a middle-aged woman presenting epigastric discomfort, hepatomegaly, biochemical signs of cholestasis, bone marrow plasmocytosis and Bence Jones proteinuria. Percutaneous liver biopsy disclosed kappa light chain deposition disease of the liver and fine needle aspiration of abdominal fat showed amyloid substance. Renal blood chemistries and urinalysis were repeatedly normal. To our knowledge, this is the first reported case of kappa light chain deposition disease of the liver and concomitant amyloidosis without renal involvement as the first manifestation of plasma cell dyscrasia. This condition should be considered in the differential diagnosis of intrahepatic cholestatic liver disease.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Paraproteinemias
/
Cadenas kappa de Inmunoglobulina
/
Enfermedad Hepática Inducida por Sustancias y Drogas
/
Amiloidosis
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Eur J Gastroenterol Hepatol
Asunto de la revista:
GASTROENTEROLOGIA
Año:
1998
Tipo del documento:
Article
País de afiliación:
Italia