Nonspecific early protective immunity in Francisella and Listeria infections can be dependent on lymphocytes.
Infect Immun
; 66(7): 3467-9, 1998 Jul.
Article
en En
| MEDLINE
| ID: mdl-9632626
ABSTRACT
Normal mice, but not lymphocyte-deficient or B-cell-deficient mice, given a sublethal infection of Francisella tularensis LVS survive a secondary lethal challenge of more than 10,000 50% lethal doses given 3 days later. In this work, we show that similar early protection that is also strongly lymphocyte dependent operates in Listeria monocytogenes infection. Since sublethal infection with either LVS or L. monocytogenes protects against heterologous lethal challenge, this early protection is nonspecific.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tularemia
/
Linfocitos
/
Listeriosis
Límite:
Animals
Idioma:
En
Revista:
Infect Immun
Año:
1998
Tipo del documento:
Article
País de afiliación:
Estados Unidos