Multiple squamous cell carcinomas of the skin during long-term treatment with hydroxyurea.
Eur J Dermatol
; 8(2): 114-5, 1998 Mar.
Article
en En
| MEDLINE
| ID: mdl-9649662
ABSTRACT
Hydroxyurea is a chemotherapeutic agent used extensively for myeloproliferative disorders. Cutaneous side effects have been described during long-term hydroxyurea treatment. We described the occurrence of multiple squamous cell skin carcinomas in a patient treated with hydroxyurea for chronic myelogenous leukemia. The lesions were removed and the hematological therapy switched to busulfan. In a previously reported case, the development of cutaneous epithelial cancers required the discontinuation of hydroxyurea, in addition to the surgical excision of the neoplastic lesions. Since squamous cell carcinoma is a malignant cutaneous neoplasm that can metastatize, the surveillance of skin changes is advisable during hydroxyurea treatment.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
/
Carcinoma de Células Escamosas
/
Leucemia Mielógena Crónica BCR-ABL Positiva
/
Neoplasias Primarias Secundarias
/
Hidroxiurea
/
Antineoplásicos
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Eur J Dermatol
Asunto de la revista:
DERMATOLOGIA
Año:
1998
Tipo del documento:
Article