Hematopoietic growth factors and transfusion medicine.

ABSTRACT

At least 20 different hematopoietic drugs (see Table 1) are currently under investigation. These most likely will impact on all aspects of transfusion therapy. Which agents to use and in what combinations will be the subject of scrutiny for many years to come as scientists try to recreate and enhance the process of hematopoiesis. Perhaps someday blood cells and hematopoietic progenitor cells can be manufactured for therapy with genetically selected phenotypes to avoid immune destruction and rejection. If this comes to pass, blood donations as we know them today, as a valuable adjunct to medical care, will fade into history, supplanted by the use of hematopoietic growth factors.