The varicella-zoster virus and multiple sclerosis.
J Clin Epidemiol
; 51(7): 533-5, 1998 Jul.
Article
en En
| MEDLINE
| ID: mdl-9674659
ABSTRACT
This article is a review of the evidence suggesting a unique relationship between the varicella-zoster virus (as a possible antigen or antigen mimic) and multiple sclerosis (MS). Both MS and varicella have increased prevalences in temperate zones and both are rare in countries closer to the equator. Migration studies suggest an infectious agent acquired prior to age 14 plays a role in the risk of subsequent MS. Hutterites, who educate their children at home, have less varicella, MS, and herpes zoster than their neighbors and have the appropriate reduced varicella-zoster seropositivity matching these clinical observations. Paradoxically, patients with MS report more herpes zoster, and at an earlier age and more often, than a group of non-MS patients.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Varicela
/
Herpes Zóster
/
Esclerosis Múltiple
Tipo de estudio:
Etiology_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Humans
/
Infant
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Clin Epidemiol
Asunto de la revista:
EPIDEMIOLOGIA
Año:
1998
Tipo del documento:
Article
País de afiliación:
Canadá