Oral administration of pectin-rich plant extract enhances C3 and C4 complement concentration in woman colostrum.
Reprod Nutr Dev
; 38(3): 255-60, 1998.
Article
en En
| MEDLINE
| ID: mdl-9698276
ABSTRACT
C3 and C4 components of the complement are normally present in human colostrum. These compounds are natural antibacterial agents. Pectin-rich plant extracts have been shown to induce prolactin release and milk synthesis when administered by the oral route in rat. In the present work, extract from a plant rich in pectin, Gossypium herbaceum was given orally to women 2 days after parturition. The extract enhanced concentration of C3 and C4 in colostrum but did not modify the total hemolytic complement activity (TCH50). No change in the concentration of the three compounds was observed in serum of the treated women. Control experiments showed that a treatment by placebo had no effect on colostrum composition. These data suggest that pectin-rich plant extracts favour transfer of C3 and C4 from blood to colostrum by an unknown mechanism. This observation suggests that some plant extracts might be used to reinforce the antibacterial activity of human colostrum.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Complemento C3
/
Complemento C4
/
Extractos Vegetales
/
Pectinas
/
Calostro
Tipo de estudio:
Clinical_trials
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Reprod Nutr Dev
Año:
1998
Tipo del documento:
Article
País de afiliación:
Irán