[Analysis of the biological characteristics of primary HIV-1 isolates using the main components method]. / Analiz biologicheskikh kharakteristik pervichnykh izoliatov VICh-1 s pomoshch'iu metoda glavnykh komponent.

ABSTRACT

The principal component method is verified for analysis of categorized biological characteristics of HIV-1 variants. Thirty wild isolates of HIV-1 are studied. The method notably facilitated comparative analysis of a large scope of experimental data. Using this method, it is possible to detect a relationship between the biological characteristics and results of other taxonomic schemes, to distinguish the factors restricting the biological signs, to single out the most informative signs for describing a given set of isolates, and to define the criteria for comparing the properties of two sets of virus isolates and selecting the isolates notably differing from each other for more thorough phenotyping.