Prospective comparison of single-zone and multizone laser in situ keratomileusis for the correction of low myopia.
Ophthalmology
; 105(8): 1504-11, 1998 Aug.
Article
en En
| MEDLINE
| ID: mdl-9709766
ABSTRACT
OBJECTIVE:
This study aimed to determine whether there is a true difference in predictability between single-zone and multizone laser in situ keratomileusis (LASIK) for the correction of low myopia or whether any difference in predictability is because of a need for separate clinical nomograms for the two treatments.DESIGN:
A prospective, randomized, clinical trial.PARTICIPANTS:
Fourteen surgeons and 190 eyes of 95 patients with myopia who desired surgical correction of myopia ranging from -2.00 to -7.00 diopters (D) participated. INTERVENTION Fellow eyes of patients with myopia undergoing bilateral simultaneous LASIK were randomized to single-zone and multizone ablation. Astigmatism was not corrected at the time of LASIK. MAIN OUTCOMEMEASURES:
Predictability, postoperative videokeratography, and contrast sensitivity were assessed at 3 months after surgery.RESULTS:
At 3 months, r2 values relating laser setting to change in spherical equivalent refraction were 0.78 for single-zone and 0.76 for multizone ablation; mean outcome with respect to intended was -0.84 D (0.65 standard deviation [SD]) for single-zone and -0.62 D (0.78 SD) for multizone eyes (P = 0.035). There was no relationship between single-zone and multizone ablation and the likelihood of asymmetric postoperative videokeratography (P = 0.83). The only difference in contrast sensitivity was a significantly greater decrease in log contrast for multizone eyes at 12 cyc/deg under undilated conditions.CONCLUSIONS:
There is no true difference in predictability between single-zone and multizone LASIK for the correction of low myopia. Separate clinical nomograms for single-zone and multizone LASIK should eliminate the difference in predictability that was observed in this clinical trial.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trasplante de Córnea
/
Córnea
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Terapia por Láser
/
Miopía
Tipo de estudio:
Clinical_trials
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Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Ophthalmology
Año:
1998
Tipo del documento:
Article
País de afiliación:
Estados Unidos