Catecholaminergic nerve fibres in normal and alkali-burned rabbit cornea.
Can J Ophthalmol
; 33(5): 259-63, 1998 Aug.
Article
en En
| MEDLINE
| ID: mdl-9740954
ABSTRACT
BACKGROUND:
In recent years anatomic research has demonstrated the presence of various types of nerve fibre in the cornea. The purpose of this study was to investigate the distribution of catecholaminergic fibres in various corneal layers and to study the effects of an experimental superficial corneal lesion on the pattern of catecholaminergic nerve fibre distribution in the various corneal layers.METHODS:
Three weeks after the creation of an alkali burn in the centre of the right cornea of five albino rabbits, the animals were killed, and histologic sections from the cornea of both eyes were stained for observation of catecholaminergic nerve fibres and photographed on black-and-white film. The photographs were examined using the Quantimet image analyser (Leica).RESULTS:
Catecholaminergic nerve fibres were observed in the corneal epithelium and the deep stromal layers. Sections from injured cornea showed a drastic reduction in epithelial and superficial stromal catecholaminergic nerve fibres, whereas the nerve fibres in the endothelium and deep stroma were not damaged.INTERPRETATION:
Although catecholaminergic nerve fibres were observed in all corneal layers, the pattern of catecholaminergic fibres following the creation of a superficial lesion of the cornea seems to suggest that the superficial and deep nerve fibres may have a different distribution.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quemaduras Químicas
/
Quemaduras Oculares
/
Fibras Colinérgicas
/
Lesiones de la Cornea
Límite:
Animals
Idioma:
En
Revista:
Can J Ophthalmol
Año:
1998
Tipo del documento:
Article
País de afiliación:
Italia