["Catatonic dilemma". Therapy with lorazepam and clozapine]. / "Katatones Dilemma". Therapie mit Lorazepam und Clozapin.
Nervenarzt
; 69(9): 818-22, 1998 Sep.
Article
en De
| MEDLINE
| ID: mdl-9789276
ABSTRACT
We are reporting on a patient with a schizoaffective disorder (ICD 10F25.1), whose catatonic symptoms deteriorated while receiving high-potency neuroleptic drugs in combination with anticholinergic medication. Initially there was a "catatonic dilemma", i.e. it was not possible to differentiate between the morbigenous and pharmacogenic (malignant neuroleptic syndrome) etiology of the catatonic symptoms. Catatonic symptoms were successfully treated with a combination of lorazepam and clozapine. The severe catatonic syndrome was found to be a neuroleptic-induced deterioration of a primary morbogenous catatonic syndrome. Thus, this case also suggests that the malignant neuroleptic syndrome and neuroleptic non-responsive catatonia may not be two different disease entities but that catatonia under neuroleptic medication is caused by the interaction of individual disposition, morbigenous and pharmacogenic factors.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Esquizofrenia Catatónica
/
Antipsicóticos
/
Ansiolíticos
/
Clozapina
/
Lorazepam
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
De
Revista:
Nervenarzt
Año:
1998
Tipo del documento:
Article