Hyponatremia in a patient with chronic inflammatory disease.
Intern Med
; 37(9): 792-5, 1998 Sep.
Article
en En
| MEDLINE
| ID: mdl-9804092
ABSTRACT
A 66-year-old man was admitted with destructive arthropathy, and calcium pyrophosphate dihydrate was demonstrated in the synovial fluid specimen. He was found to have a hyponatremia. The serum sodium concentration was 121 mmol/l, plasma arginine vasopressin (AVP) 6.6 pmol/l, and serum interleukin (IL)-6 96 pg/l. The clinical findings suggest the diagnosis of syndrome of inappropriate secretion of antidiuretic hormone (SIADH). However, destructive arthropathy with increased values of C-reactive protein and IL-6 is the only background of SIADH in this patient. We suggest the possibility that IL-6 produced at inflammatory lesions may have stimulated an excessive release of AVP resulting in the hyponatremia and hypochloremia of SIADH.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Artritis
/
Arginina Vasopresina
/
Hiponatremia
/
Síndrome de Secreción Inadecuada de ADH
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Intern Med
Asunto de la revista:
MEDICINA INTERNA
Año:
1998
Tipo del documento:
Article