Oxytocin receptor antagonists. Update.
Clin Perinatol
; 25(4): 859-71, vi, 1998 Dec.
Article
en En
| MEDLINE
| ID: mdl-9891619
ABSTRACT
For over three decades, scientists in a number of different laboratories have worked to design peptide analogues of oxytocin (OT) selective for the oxytocin receptor. Although there has been some interest in their use for treatment of dysmenorrhea, the principal clinical venue for such agents has been thought to lie in treatment of preterm labor. A major difficulty in identifying the clinical role for an OT antagonist had been our incomplete understanding of the role of OT in both term and preterm labor. This article begins with a review of the current understanding of the role of OT in the initiation and maintenance of labor in the human.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trabajo de Parto
/
Oxitocina
/
Vasotocina
/
Tocolíticos
/
Receptores de Oxitocina
/
Trabajo de Parto Prematuro
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Clin Perinatol
Año:
1998
Tipo del documento:
Article
País de afiliación:
Estados Unidos