Misuse of drugs in acute diarrhoea in under-five children.

ABSTRACT

This was a community based, thirty cluster survey, carried out in Chittagong metropolitan area of Bangladesh, aimed to determine the extent of misuse of drugs in acute diarrhoea among under-five children. Data were collected from 360 mothers whose under-five children had suffered from acute diarrhoea during the preceding two weeks of interview. Data were pertained to type and duration of diarrhoea and treatment received. There were 339(94.2%) cases of acute watery diarrhoea and 21 (5.8%) cases of dysentery i.e. blood in stool. The mean duration of the diarrhoeal episode was 3.17 +/- 1.69 days (95% CI, 2.99-3.34). Three hundred twenty eight (91.1%) cases received treatment. There was a total of 401 consultations, out of which 328(81.8%) had first, 69(17.2%) had second and 4(1.0%) had third consultations. The first and second treatment were provided predominantly by care-providers (43.3%) and physicians (5.5%) respectively. Only 82(26.7%) cases of acute watery diarrhoea received WHO recommended treatment and only 5(23.8%) cases of dysentery received appropriate antibiotics. The rest 241(73.5%) cases received inappropriate treatment either antibiotic or drugs other than WHO recommendation. The average number of drugs prescribed per patient was 1.5 during the episode. The commonly prescribed drugs were metronidazole (38.6%) and antibiotics (17.3%). Those who consulted health professionals were at 5.7 times higher risk of receiving drugs. The mean duration of the episode of acute watery diarrhoea was increased significantly when drug is used in the treatment. It is concluded that there was high prevalence of misuse of drugs in the treatment of acute diarrhoea among under-five children which calls for intervention to improve the prescribing pattern as per WHO recommendation.

ABSTRACT

PIP This study determines the extent of drug misuse in acute diarrhea among under-five children in Chittagong, Bangladesh. Data were collected from 360 mothers whose under-five children suffered acute diarrhea 2 weeks prior to interview. Information gathered pertained to the type and duration of diarrhea and the treatment received. The were 339 cases of acute watery diarrhea and 21 cases of dysentery (i.e., bloody stools). The mean duration of the diarrheal episode lasted 3.17 +or- 1.69 days. From the total cases, only 328 received treatment. Moreover, only 82 cases of acute watery diarrhea received WHO recommended treatment and only 5 from the total number of cases received appropriate antibiotic treatment, while the 241 cases received inappropriate medication. The commonly prescribed drugs were metronidazole and antibiotics. Unfortunately, those who consulted health professionals were at 5.7 times higher risk of receiving the drugs and even experienced longer episodes of acute diarrhea. Results suggest that there is a significant misuse of antidiarrheal drugs among under-five children.