Your browser doesn't support javascript.
loading
SARS-CoV-2 Delta breakthrough infections in vaccinated patients
Jing Zou; Xuping Xie; Mingru Liu; Pei-Yong Shi; Ping Ren.
Afiliación
  • Jing Zou; University of Texas Medical Branch
  • Xuping Xie; University of Texas Medical Branch
  • Mingru Liu; University of Texas Medical Branch
  • Pei-Yong Shi; University of Texas Medical Branch
  • Ping Ren; University of Texas Medical Branch
Preprint en En | PREPRINT-BIORXIV | ID: ppbiorxiv-488092
ABSTRACT
The continuous emergence of SARS-CoV-2 variants with increased transmission and immune evasion has caused breakthrough infections in vaccinated population. It is important to determine the threshold of neutralizing antibody titers that permit breakthrough infections. Here we tested the neutralization titers of vaccinated patients who contracted Delta variant. All 75 patients with Delta breakthrough infections exhibited neutralization titers (NT50) of less than 70. Among the breakthrough patients, 76%, 18.7%, and 5.3% of them had the NT50 ranges of <20, 20-50, and 50-69, respectively. These clinical laboratory results have implications in vaccine strategy and public health policy.
Licencia
cc_by_nc_nd
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-BIORXIV Tipo de estudio: Prognostic_studies Idioma: En Año: 2022 Tipo del documento: Preprint
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-BIORXIV Tipo de estudio: Prognostic_studies Idioma: En Año: 2022 Tipo del documento: Preprint