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SARS-CoV-2 seroprevalence in a rural and urban community household cohort in South Africa, after the third wave, April-November 2021
Jackie Kleynhans; Stefano Tempia; Nicole Wolter; Anne von Gottberg; Jinal N. Bhiman; Amelia Buys; Jocelyn Moyes; Meredith L. McMorrow; Kathleen Kahn; F. Xavier Gomez-Olive; Stephen Tollman; Neil A. Martinson; Floidy Wafawanaka; Limakatso Lebina; Jacques du Toit; Waasila Jassat; Mzimasi Neti; Marieke Brauer; Cheryl Cohen; - the PHIRST-C Group.
Afiliación
  • Jackie Kleynhans; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Afri
  • Stefano Tempia; Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America. Influenza Program, Centers for Disease Control and P
  • Nicole Wolter; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Afri
  • Anne von Gottberg; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Afri
  • Jinal N. Bhiman; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Afri
  • Amelia Buys; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Afri
  • Jocelyn Moyes; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Afri
  • Meredith L. McMorrow; Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America. Influenza Program, Centers for Disease Control and P
  • Kathleen Kahn; MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), Faculty of Health Sciences, School of Public Health, University of the Witwatersr
  • F. Xavier Gomez-Olive; MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), Faculty of Health Sciences, School of Public Health, University of the Witwatersr
  • Stephen Tollman; MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Science, University of the Witwatersra
  • Neil A. Martinson; Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Johannesburg, South Africa. Johns Hopkins University Center for TB Research, Baltimore, Mar
  • Floidy Wafawanaka; MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), Faculty of Health Sciences, School of Public Health, University of the Witwatersr
  • Limakatso Lebina; Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Johannesburg, South Africa. Africa Health Research Institute, Durban, South Africa. Africa
  • Jacques du Toit; MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), Faculty of Health Sciences, School of Public Health, University of the Witwatersr
  • Waasila Jassat; Division of Public Health Surveillance and Response, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South
  • Mzimasi Neti; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Afri
  • Marieke Brauer; Immunology Department, National Reference Laboratory, Ampath Pathology, Pretoria, South Africa
  • Cheryl Cohen; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Afri
  • - the PHIRST-C Group;
Preprint en Inglés | medRxiv | ID: ppmedrxiv-22270772
ABSTRACT
By November 2021, after the third SARS-CoV-2 wave in South Africa, seroprevalence was 60% (95%CrI 56%-64%) in a rural and 70% (95%CrI 56%-64%) in an urban community; highest in individuals aged 13-18 years. High seroprevalence prior to Omicron emergence may have contributed to reduced severity observed in the 4th wave. Article Summary LineIn South Africa, after a third wave of SARS-CoV-2 infections, seroprevalence was 60% in a rural and 70% in an urban community, with case-to-infection, - hospitalization and -fatality ratios similar to the second wave.
Licencia
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Texto completo: Disponible Colección: Preprints Base de datos: medRxiv Tipo de estudio: Cohort_studies / Estudio observacional / Estudio pronóstico Idioma: Inglés Año: 2022 Tipo del documento: Preprint
Texto completo: Disponible Colección: Preprints Base de datos: medRxiv Tipo de estudio: Cohort_studies / Estudio observacional / Estudio pronóstico Idioma: Inglés Año: 2022 Tipo del documento: Preprint
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