Study on molecular mechanism of circulating tumor cell clusters promoting hematogenous metastasis / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 602-606, 2021.
Article
en Zh
| WPRIM
| ID: wpr-1014405
Biblioteca responsable:
WPRO
ABSTRACT
Tumor metastasis is an important cause of death in tumor patients. Once metastasis occurs, cancer will become more difficult to treat. Many studies have observed circulating tumor cells (CTCs) in the circulatory system of patients with metastasis. CTCs may occasionally appear in the form of clusters during the process of hematogenous metastasis. These aggregated tumor cell clusters have higher efficacy than the single CTC. The development of circulating tumor cell cluster capture technology provides new insights into tumor metastasis. The molecular mechanism of CTC clusters formation and their role in tumor hematogenous metastasis are discussed here, and their use as biomarkers and target in therapy is evaluated.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Año:
2021
Tipo del documento:
Article