Delayed presentation of aggravation of thyrotoxicosis after radioactive iodine therapy at Graves disease / 영남의대학술지
Yeungnam University Journal of Medicine
; : 148-151, 2014.
Article
en Ko
| WPRIM
| ID: wpr-106563
Biblioteca responsable:
WPRO
ABSTRACT
Radioactive iodine (RAI) therapy is widely used for the treatment of Graves disease. After RAI therapy, 44% become hypothyroid and up to 28% remain hyperthyroid. The development of thyrotoxicosis after RAI therapy is believed to be mediated by 2 different mechanisms a transient increased release of thyroid hormone due to radiation thyroiditis and the rare development of Graves disease due to the formation of antibodies to the thyroid-associated antigens released from the damaged follicular cells. A 55-year-old woman was hospitalized with severe headache, weight loss, and palpitation. She received a dose of 7 mCi of RAI (I-131) about 6 weeks earlier. Thyroid function test showed 7.98 ng/dL free T4, >8 ng/mL T3, <0.08 microIU/L thyroid stimulating hormone, and high titer thyroid stimulating immunoglobulin (TSI) (85.8 IU/L). She improved with propylthiouracil, propranolol, and steroid treatment. The TSI, however, was persistently elevated for 11 months.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Propranolol
/
Propiltiouracilo
/
Pruebas de Función de la Tiroides
/
Glándula Tiroides
/
Tiroiditis
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Tirotoxicosis
/
Tirotropina
/
Pérdida de Peso
/
Enfermedad de Graves
/
Inmunoglobulinas Estimulantes de la Tiroides
Límite:
Female
/
Humans
Idioma:
Ko
Revista:
Yeungnam University Journal of Medicine
Año:
2014
Tipo del documento:
Article