Lymphomatoid Granulomatosis: CT and FDG-PET Findings
Korean Journal of Radiology
; : 671-678, 2011.
Article
en En
| WPRIM
| ID: wpr-155127
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE:
Lymphomatoid granulomatosis (LG) is a rare, aggressive extranodal Epstein-Barr virus (EBV)-positive B-cell lymphoproliferative disease. The purpose of our study was to analyze the CT and fluorodeoxyglucose positron emission tomography (FDG-PET) findings of pulmonary LG. MATERIALS ANDMETHODS:
Between 2000 and 2009, four patients with pathologically proven pulmonary LG and chest CT were identified. Two of these patients also had FDG-PET. Imaging features of LG on CT and PET were reviewed.RESULTS:
Pulmonary nodules or masses with peribronchovascular, subpleural, and lower lung zonal preponderance were present in all patients. Central low attenuation (4 of 4 patients), ground-glass halo (3 of 4 patients), and peripheral enhancement (4 of 4 patients) were observed in these nodules and masses. An air-bronchogram and cavitation were seen in three of four patients. FDG-PET scans demonstrated avid FDG uptake in the pulmonary nodules and masses.CONCLUSION:
Pulmonary LG presents with nodules and masses with a lymphatic distribution, as would be expected for a lymphoproliferative disease. However, central low attenuation, ground-glass halo and peripheral enhancement of the nodules/masses are likely related to the angioinvasive nature of this disease. Peripheral enhancement and ground-glass halo, in particular, are valuable characteristic not previously reported that can help radiologists suggest the diagnosis of pulmonary LG.Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Biopsia con Aguja
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Tomografía Computarizada por Rayos X
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Radiofármacos
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Fluorodesoxiglucosa F18
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Tomografía de Emisión de Positrones
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Neoplasias Pulmonares
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Granulomatosis Linfomatoide
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Korean Journal of Radiology
Año:
2011
Tipo del documento:
Article