Endoscopic Management of Gastroesophageal Reflux Disease: Revisited
Clinical Endoscopy
; : 408-416, 2016.
Article
en En
| WPRIM
| ID: wpr-205875
Biblioteca responsable:
WPRO
ABSTRACT
Gastroesophageal reflux disease (GERD) is defined by the presence of troublesome symptoms resulting from the reflux of gastric contents. The prevalence of GERD is increasing globally. An incompetent lower esophageal sphincter underlies the pathogenesis of GERD. Proton pump inhibitors (PPIs) form the core of GERD management. However, a substantial number of patients do not respond well to PPIs. The next option is anti-reflux surgery, which is efficacious, but it has its own limitations, such as gas bloating, inability to belch or vomit, and dysphagia. Laparoscopic placement of magnetic augmentation device is emerging as a useful alternative to conventional anti-reflux surgery. However, invasiveness of a surgical procedure remains a concern for the patients. The proportion of PPI non-responders or partial responders who do not wish for anti-reflux surgery defines the ‘treatment gap’ and needs to be addressed. The last decade has witnessed the fall and rise of many endoscopic devices for GERD. Major endoscopic strategies include radiofrequency ablation and endoscopic fundoplication devices. Current endoscopic devices score high on subjective improvement, but have been unimpressive in objective improvement like esophageal acid exposure. In this review, we discuss the current endoscopic anti-reflux therapies and available evidence for their role in the management of GERD.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Trastornos de Deglución
/
Reflujo Gastroesofágico
/
Prevalencia
/
Ablación por Catéter
/
Fundoplicación
/
Esfínter Esofágico Inferior
/
Endoscopía
/
Inhibidores de la Bomba de Protones
Tipo de estudio:
Prevalence_studies
Límite:
Humans
Idioma:
En
Revista:
Clinical Endoscopy
Año:
2016
Tipo del documento:
Article