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Isolated Spinal Cord Neurosarcoidosis Diagnosed by Cord Biopsy and Thalidomide Trial
Article en En | WPRIM | ID: wpr-211264
Biblioteca responsable: WPRO
ABSTRACT
We report a case of 54-yr-old woman who presented with 4-extremities weakness and sensory changes, followed by cervical spinal cord lesion in magnetic resonance imaging. Based on the suspicion of spinal tumor, spinal cord biopsy was performed, and the histology revealed multinucleated giant cells, lymphocytes and aggregated histiocytes within granulomatous inflammation, consistent with non-caseating granuloma seen in sarcoidosis. The patient was treated with corticosteroid, immunosuppressant and thalidomide for years. Our case indicates that diagnosis of spinal cord sarcoidosis is challenging and may require histological examination, and high-dose corticosteroid and immunosuppressant will be a good choice in the treatment of spinal cord sarcoidosis, and the thalidomide has to be debated in the spinal cord sarcoidosis.
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Texto completo: 1 Base de datos: WPRIM Asunto principal: Sarcoidosis / Médula Espinal / Enfermedades de la Médula Espinal / Talidomida / Biopsia / Imagen por Resonancia Magnética / Enfermedades del Sistema Nervioso Central / Corticoesteroides / Inmunosupresores Tipo de estudio: Diagnostic_studies Límite: Female / Humans Idioma: En Revista: Journal of Korean Medical Science Año: 2011 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Asunto principal: Sarcoidosis / Médula Espinal / Enfermedades de la Médula Espinal / Talidomida / Biopsia / Imagen por Resonancia Magnética / Enfermedades del Sistema Nervioso Central / Corticoesteroides / Inmunosupresores Tipo de estudio: Diagnostic_studies Límite: Female / Humans Idioma: En Revista: Journal of Korean Medical Science Año: 2011 Tipo del documento: Article