Dyslipidemia Treatment in Diabetes Mellitus Patients / 대한내과학회지

ABSTRACT

Cardiovascular disease (CVD) is the major cause of mortality and morbidity in patients with type 2 diabetes mellitus. The increased risk of CVD in subjects with type 2 diabetes mellitus involves multiple factors, including hypertension, smoking, albuminuria, and hypercholesterolemia. Of these, hypercholesterolemia is amenable to intervention. A large body of research ranging from molecular to population studies indicates that elevated low-density-lipoprotein cholesterol (LDL-C) is a major predictor of CVD, including in the population with diabetes. Despite available therapies and increased attention to hypercholesterolemia, many patients fail to achieve the LDL-C goals. A patient-tailored approach to dyslipidemia therapy, as determined by baseline LDL-C levels, is an effective strategy for achieving target LDL-C levels.