Serum Albumin Level Correlates with Disease Severity in Patients with Hemorrhagic Fever with Renal Syndrome
Journal of Korean Medical Science
; : 696-700, 2003.
Article
en En
| WPRIM
| ID: wpr-221853
Biblioteca responsable:
WPRO
ABSTRACT
Hypoalbuminemia frequently occurs in Hemorrhagic Fever with Renal Syndrome (HFRS), but clinical significance of hypoalbuminemia is not well known. This study was designed to evaluate hypoalbuminemia as a marker of severity of disease in patients with HFRS. We evaluated the relationship between the level of serum albumin and clinical parameters representing the severity of disease in 144 patients with HFRS. The patients were divided into three groups based on the level of serum albumin; Group I (normal serum albumin), Group II (serum albumin or =3.0 g/dL), and Group III (serum albumin <3.0 g/dL). Of the total of 144 patients, 42 patients (29.2%) were categorized as Group I, 39 patients (27.1%) as Group II, and 63 patients (43.8%) as Group III. Group III had a higher rate of incidence in episode of hypotension, pulmonary edema than did Group I and Group II. The lowest level of serum albumin was positively correlated with platelet count (r=0.505, p<0.001) and was negatively correlated with leukocyte count (r=-0.329, p<0.001), BUN (r=-0.484, p<0.001), serum creatinine (r=-0.394, p<0.001), and AST (r=-0.251, p=0.002). Our data suggest that hypoalbuminemia frequently occurs in the acute stage of HFRS, and level of serum albumin is associated with the disease severity of HFRS.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Albúmina Sérica
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Estudios Retrospectivos
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Resultado del Tratamiento
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Técnica del Anticuerpo Fluorescente Indirecta
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Hipoalbuminemia
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Fiebres Hemorrágicas Virales
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Enfermedades Renales
Tipo de estudio:
Observational_studies
Límite:
Adolescent
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Adult
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Aged
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Aged80
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Child
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Female
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Humans
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Male
Idioma:
En
Revista:
Journal of Korean Medical Science
Año:
2003
Tipo del documento:
Article