Cytotoxicity study of heparin coated polyvinyl chloride material / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 739-741, 2005.
Article
en Zh
| WPRIM
| ID: wpr-238352
Biblioteca responsable:
WPRO
ABSTRACT
In this study, heparin ionically coated polyvinyl chloride (PVC) material was prepared by heparin-benzalkonium chloride complex (Group A), heparin-benzalkonium bromide complex (Group B) and heparin-polyethyleneimine compound (Group C). Cytotoxicity evaluation was conducted by direct cell contact evaluation and MTT colorimetry method. The results showed Group A and Group B caused L-929 cells to die out while Group C showed good compatibility with cells. The OD levels of Group A and B were lower than that of the Group C in MTT test. Method A and method B of heparin coating had remarkable cytotoxicity, while method C had little cytotoxicity and could be further studied for clinical use.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Cloruro de Polivinilo
/
Ensayo de Materiales
/
Heparina
/
Células Cultivadas
/
Materiales Biocompatibles Revestidos
/
Biología Celular
/
Toxicidad
/
Fibroblastos
Límite:
Animals
Idioma:
Zh
Revista:
Journal of Biomedical Engineering
Año:
2005
Tipo del documento:
Article