Studies on lignan constituents of Clematis parviloba / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents of the stems of Clematis parviloba.</p><p><b>METHOD</b>The compounds were isolated and purified by repeated column chromatography with silica gel, Sephadex LH-20 and HPLC. Their structures were identified by spectroscopic data together with physical and chemical property.</p><p><b>RESULT</b>Ten compounds have been isolated from the stems of C. parviloba, and identified as (+) pinoresionol (1), (+) pinoresionol-4'-O-p-D-glucopyranoside (2), ( +) pinoresionol4, 4'-O-bis-beta-D-glucopyranoside (3), (-) syringaresinol (4), (+) syringaresinol-4'-O-beta-D-glucopyranoside (5), (-)episyringaresinol (6), (+) medioresinol-4'-O-beta-D-glucopyranoside (7), (+) lariciresinol-4-O-beta-D-glucopyranoside (8), (+) lariciresinol-4'-O-beta-D-glucopyranoside (9), (+) lariciresinol-4, 4'-O-bis-beta-D-glucopyranoside (10), respectively.</p><p><b>CONCLUSION</b>Compounds 6, 7 were isolated from this genus for the first time, and the other ones were isolated from this plant for the first time.</p>