Progress in TcpC research / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 481-485, 2013.
Article
en Zh
| WPRIM
| ID: wpr-252602
Biblioteca responsable:
WPRO
ABSTRACT
TcpC is a homolog of the Toll/interleukin-1 receptor (TIR) domain and is secreted by uropathogenic E. coli strain CFT073. TcpC can bind to MyD88, hereby exerting inhibitory effects on macrophages. TcpC represents an important virulence factor that promotes bacterial survival and pathogenicity. TcpC plays a critical role in urinary tract infection, particularly in the pathogenesis of pyelonephritis. In this review,the progress and prospects in TcpC research are discussed.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Fisiología
/
Pielonefritis
/
Infecciones Urinarias
/
Virulencia
/
Proteínas de Escherichia coli
/
Factores de Virulencia
/
Escherichia coli
/
Microbiología
Límite:
Animals
/
Humans
Idioma:
Zh
Revista:
Journal of Zhejiang University. Medical sciences
Año:
2013
Tipo del documento:
Article