Prognostic factors of penis-sparing surgery for early-stage penile cancer / 中华男科学杂志
National Journal of Andrology
; (12): 401-405, 2016.
Article
en Zh
| WPRIM
| ID: wpr-262339
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the factors influencing the prognosis of penis-sparing surgery (PSS) for early-stage penile cancer.</p><p><b>METHODS</b>We retrospectively studied the clinical data about 45 cases of early-stage penile cancer treated by PSS from January 2007 to December 2014. We calculated the rate of local recurrence-free survival by the Kaplan-Meier method, and conducted univariate and multivariate COX regression analyses on the relevant factors including the patient's age, marital status, tumor location, tumor size, postoperative sexual life, histological grade, and TNM stage.</p><p><b>RESULTS</b>One-year and three-year local recurrence-free survival rates were 95.5% and 52.2%, respectively. Multivariate analysis demonstrated that the histological grade (P = 0.039) and postoperative sexual life (P = 0.049) were independent factors for the prognosis of PSS. Logistic regression showed the patients age to be significantly associated with histological grade (P = 0.014).</p><p><b>CONCLUSION</b>Histological grade and postoperative sexual life are important independent prognostic factors of PSS for early-stage penile cancer, and the patients age is associated with the prognosis of PSS through its influence on the tumor grade.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Neoplasias del Pene
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Pene
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Pronóstico
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Calidad de Vida
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Cirugía General
/
Modelos Logísticos
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Modelos de Riesgos Proporcionales
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Análisis Multivariante
/
Estudios Retrospectivos
/
Factores de Edad
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspecto:
Patient_preference
Límite:
Humans
/
Male
Idioma:
Zh
Revista:
National Journal of Andrology
Año:
2016
Tipo del documento:
Article