Identification of constituents in Suanzaoren tang by LC-Q-TOF-MS and LC-IT-MS / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 457-465, 2014.
Article
en Zh
| WPRIM
| ID: wpr-287565
Biblioteca responsable:
WPRO
ABSTRACT
LC-Q-TOF-MS and LC-IT-MS in positive and negative ion mode were applied to simultaneously characterize the constituents in Suanzaoren tang. Analysis was performed on an Agilent Zorbax SB-C18, Rapid Resolution HT column(4.6 mmx 50 mm, 1. 8 micro m) with gradient elution of acetonitrile(A) -aqueous solution containing 0. 05% formic acid(B) at a flow rate of 0. 6 mL min(-1) and the column temperature was 30 degreesC. By comparing MS fragmentation, accurate molecular weight, literature date and standard compounds information, a total of48 compounds were successfully identified or speculated. The origins of these compounds were assigned to the corresponding Chinese medicine. Thirty-one compounds were reported in Suanzaoren tang for the first time. LC-Q-TOF-MS combined with LC-IT-MS is a simple and rapid tool for the identification of constituents of Suanzaoren tang, and the results could provide evidence for the research on quality combined and effective constituents of Suanzaoren tang.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Compuestos Orgánicos
/
Espectrometría de Masas
/
Medicamentos Herbarios Chinos
/
Química
/
Cromatografía Liquida
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2014
Tipo del documento:
Article