Immobilization of CD34 antibodies onto ethylene-vinyl acetate copolymer coatings and in vitro cell attachments / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 1130-1134, 2008.
Article
en Zh
| WPRIM
| ID: wpr-318199
Biblioteca responsable:
WPRO
ABSTRACT
Rapid re-endothelialization of implanted coronary artery stent is a new way for preventing restenosis. In this paper, adhesive polypeptide mimics of marine organism and antibodies potentially selective targeting with CD34 antigens on endothelial cells (ECs) were immobilized onto ethylene-vinyl acetate copolymer (EVA) coatings for improving the re-endothelialization process. The results showed that the attachments, growths, viabilities, as well as cell retentions of ECs on EVA were improved after modification. The immobilized polypeptide promoted the attachments of ECs, but overmuch polypeptide would restrict the attachments. With the increase of antibody concentration, the immobilized antibodies and cell attachments were improved.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Péptidos
/
Polivinilos
/
Venas Umbilicales
/
Adhesión Celular
/
Stents
/
Células Cultivadas
/
Química
/
Antígenos CD34
/
Materiales Biocompatibles Revestidos
/
Reestenosis Coronaria
Límite:
Humans
Idioma:
Zh
Revista:
Journal of Biomedical Engineering
Año:
2008
Tipo del documento:
Article
Pais de publicación:
CHINA
/
CN
/
REPUBLIC OF CHINA