Rational approach to the management of IV stage gastric carcinoma with hepatic metastasis / 中华胃肠外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the benefit of surgical resection on the prognosis of patients with advanced gastric carcinoma and liver metastasis.</p><p><b>METHODS</b>Data of 102 cases of advanced gastric carcinoma with liver metastases from 1993 to 2004 were studied retrospectively.</p><p><b>RESULTS</b>The half-, one- and two-year postoperative survival rates of gastric carcinoma patients with H(1) metastasis undergone palliative resections were 69%, 44% and 6% respectively, which were significantly better than those of patients not undergone resection(accepted by-pass procedure or exploratory laparotomy) (P=0.009). The half-, one- and two-year postoperative survival rates of gastric carcinoma patients with H(2) metastasis undergone palliative resections were 56%,13% and 6% respectively, which were not significantly different compared with those of patients not undergone resection(P=0.068). The half-, one- and two-year postoperative survival rates of gastric carcinoma patients with H(3) metastasis undergone palliative resections were 25%, 13% and 0, which were not significantly different compared with those of cases not undergone resection (P=0.157). Regardless of peritoneal metastases, there were no significant differences between the survival rate of resection group and that of non-resection group.</p><p><b>CONCLUSIONS</b>Gastric carcinoma patients with H(1) metastasis would benefit from palliative resection regardless of peritoneal metastasis. Gastric carcinoma patients with H(2) or H(3) metastasis are not benefit from surgical resection.</p>