Heart rate variability in children with beta-thalassemia major / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 654-656, 2011.
Article
en Zh
| WPRIM
| ID: wpr-339569
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the diagnostic value of heart rate variability (HRV) in heart dysfunction in children with beta-thalassemia major (β-TM)by examining the changes of HRV in β-TM children.</p><p><b>METHODS</b>A 24 hours Holter monitoring electrocardiogram (Holter) was performed in 21 children with β-TM and 15 healthy children (control group). The time domain and frequency domain indexes of HRV in the two groups were compared. The correlation between serum ferritin levels and HRV was evaluated.</p><p><b>RESULTS</b>The time domain indexes SDNN, rMSSD and PNN50 and the frequency domain indexes very low frequency (VLF), low frequency (LF) and high frequency (HF) in the β-TM group were significantly lower than in the control group (P<0.05). There was no correlation between serum ferritin level and HRV in children with β-TM.</p><p><b>CONCLUSIONS</b>The autonomic nerve dysfunction exists in children with β-TM. HRV analysis is useful in the prediction of early cardiac dysfunction in children with β-TM.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Fisiología
/
Sangre
/
Talasemia beta
/
Ferritinas
/
Frecuencia Cardíaca
Límite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Idioma:
Zh
Revista:
Chinese Journal of Contemporary Pediatrics
Año:
2011
Tipo del documento:
Article
Pais de publicación:
CHINA
/
CN
/
REPUBLIC OF CHINA