The genotyping and molecular evolution of varicella-zoster virus / 病毒学报
Chinese Journal of Virology
; (6): 584-590, 2012.
Article
en Zh
| WPRIM
| ID: wpr-340001
Biblioteca responsable:
WPRO
ABSTRACT
Varicella-zoster virus (VZV, Human herpesvirus 3) is a member of the family Herpesviridae, and is classified as alpha-subfamily along with HSV-1 and HSV-2. VZV is the causative agent of chicken pox (varicella) mostly in children, after which it establishes latency in the sensory ganglia with the potential to reactivate at a later time to cause shingles (zoster). Increasing molecular epidemiological studies in recent years have been performed to monitor the mutations in VZV genome, discriminate vaccine virus from wild type virus, study the phylogeny of VZV strains throughout the world, and understand the evolution of the different clades of VZV. The progress has great impact on the fields of epidemiology, virology and bioinformatics. In this review, the currently available data concerning the geographic distribution and molecular evolution of VZV clades are discussed.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Filogenia
/
Virología
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Datos de Secuencia Molecular
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Secuencia de Bases
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Clasificación
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Herpesvirus Humano 3
/
Evolución Molecular
/
Genética
/
Genotipo
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Herpes Zóster
Límite:
Animals
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Humans
Idioma:
Zh
Revista:
Chinese Journal of Virology
Año:
2012
Tipo del documento:
Article
Pais de publicación:
CHINA
/
CN
/
REPUBLIC OF CHINA