Value of Doppler echocardiography derived myocardial energy expenditure measurements in chronic heart failure patients / 中华心血管病杂志
Chinese Journal of Cardiology
; (12): 209-214, 2010.
Article
en Zh
| WPRIM
| ID: wpr-341252
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the relationship between myocardial energy expenditure (MEE) level and cardiac function in chronic heart failure (CHF) patients.</p><p><b>METHODS</b>A total of 99 CHF patients were divided into 3 groups according to the LVEF (HFNEF > or = 50%, n = 37; HFREF1 35.1% - 49.9%, n = 30; HFREF2 < or = 35%, n = 32) or the New York Heart Association (NYHA II, n = 26; III, n = 42; IV, n = 31) criteria. Thirty patients with cardiovascular disease and without CHF served as controls. Routine examinations including serum CRP (ELISA) and plasma NT-proBNP (chemiluminescence sandwich ELISA) were made on the next morning after admission; echocardiography was performed on the third day after admission. LVMW, LVMWI, RWT, LVIDd, LA, LV, LVEF, LVFS, E/A, EDT, IVRT, Tei index and MEE were measured or calculated.</p><p><b>RESULTS</b>MEE was significantly higher in HFREF patients than in controls (P < 0.01) and similar between HFNEF patients and controls (P > 0.05). MEE increased in proportion to decrease of LVEF and increase of NYHA grades in CHF patients (all P < 0.05). Bivariate analysis confirmed that MEE was significant correlated with LVMW, LVMWI, RWT, LVIDd, LA, LV, LVEF (r = -0.540, P < 0.01), LVFS (r = -0.454, P < 0.01), E/A, EDT, IVRT, Tei index, NYHA grades, CRP and NT-proBNP.</p><p><b>CONCLUSION</b>MEE derived from standard echocardiographic measurements is an effective indicator for myocardial bioenergetics and significantly correlated with cardiac function in CHF patients, especially in CHF patients with reduced LVEF.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Diagnóstico por Imagen
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Ecocardiografía Doppler
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Estudios de Casos y Controles
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Enfermedad Crónica
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Función Ventricular Izquierda
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Metabolismo Energético
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Insuficiencia Cardíaca
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Metabolismo
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Miocardio
Tipo de estudio:
Diagnostic_studies
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Health_economic_evaluation
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Observational_studies
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Risk_factors_studies
Límite:
Aged
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Cardiology
Año:
2010
Tipo del documento:
Article