The role of coronary sinus musculature on electrical conduction between left atrium and right atrium in isolated canine heart / 中华心血管病杂志
Chinese Journal of Cardiology
; (12): 834-837, 2008.
Article
en Zh
| WPRIM
| ID: wpr-355884
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate electrophysiological characteristics of the coronary sinus musculature and explore its role on electrical conduction between left atrium and right atrium in isolated canine heart.</p><p><b>METHOD</b>The electrical connections between coronary sinus, left atrium and right atrium were detected by programmed stimulation delivered at coronary sinus ostium, distal coronary sinus and lateral wall of left atrium in a Langendorff model of canine.</p><p><b>RESULTS</b>During stimulation delivered at coronary sinus ostium and distal coronary sinus, posterior wall of left atrium was firstly activated by electronic signal through coronary sinus musculature, the conduct time of coronary sinus ostium stimulation and distal coronary sinus stimulation were (44 +/- 21) ms and (41 +/- 15) ms, respectively. During stimulation delivered at lateral wall of left atrium, electronic signal was firstly observed in coronary sinus. During premature stimulation, conduction blockade of coronary sinus to left atrium was evidenced in parts of hearts, but electronic conduction of left atrium to right atrium remained stable. The ERP at the different stimulation sites of coronary sinus ostium and distal coronary sinus, posterior wall of left atrium were (122 +/- 19) ms, (114 +/- 12) ms (n = 3) and (107 +/- 17) ms (all P > 0.05).</p><p><b>CONCLUSION</b>A conduction way connecting left and right atria exists in coronary sinus which might play an important role on inducing and maintaining atrial arrhythmias under certain pathological conditions.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Fisiología
/
Seno Coronario
/
Atrios Cardíacos
/
Sistema de Conducción Cardíaco
/
Miocardio
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
Zh
Revista:
Chinese Journal of Cardiology
Año:
2008
Tipo del documento:
Article